Kelly Osbourne has quit 'Fashion Police'.

The network confirmed the news in a statement on Friday, saying: "Kelly Osbourne is departing E!'s 'Fashion Police' to pursue other opportunities, and we would like to thank her for her many contributions to the series over the past five years, during which time the show became a hit with viewers. 'Fashion Police' will return, as scheduled, on Friday, March 30th at 9:00 p.m. and no decisions have been made on her replacement."

The lilac-haired star threatened to quit on Twitter earlier this week after Giuliana's controversial comments about her friend Zendaya, 18.

But a source claims she doesn't think the show has been the same since Kathy Griffin took over from the late Joan Rivers.

The insider told the MailOnline: "Kelly stayed on the show after the beloved Joan Rivers passed away, but nothing has been the same since.

"The chemistry has not been the same between the hosts since the show came back on air and Kelly knows it's time to move on.

"This has nothing to do Giuliana. Zendaya accepted Giuliana's apology and she's already moved on to a new hair style! Even Kelly tweeted 'this too shall pass' and was over it.

"Joan was the mama bear, she stopped all the quarrels and held the show together, even when Kelly was being testy."

News of Kelly's departure comes shortly after her father Ozzy Osbourne threatened 'Access Hollywood Live' host Billy Bush, who is friends with Giuliana, on Twitter after he blasted rumours Kelly warned her not to joke she thought Zendaya's dreadlocks would "smell of patchouli or maybe weed."

The British rocker tweeted: "@BillyBush stop acting like a b****. Act like a man. Lay off Kelly or we'll be going to hospital to get my foot out of your a**. God Bless."